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Advant 16mg Tabs 14’s
KShs 1,354.00- Description
- ADVANT (Candesartan cilexetil), a prodrug, is hydrolyzed to candesartanduring absorption from the gastrointestinal tract. Candesartan is a selective AT1 subtype angiotensin II receptor antagonist. ADVANT Tablets 16mg: Each tablet contains Candesartan cilexetil 16mg. THERAPEUTIC INDICATIONS: Hypertension- ADVANT (Candesartan cilexetil) is indicated for the treatment of hypertension in adults and children 1 to < 17 years of age. It may be used alone or in combination with other antihypertensive agents. Heart Failure: -ADVANT (Candesartan cilexetil) is indicated for the treatment of heart failure (NYHA class II-IV) in adults with left ventricular systolic dysfunction(<40%) to reduce cardiovascular death and to reduce heart failurehospitalizations. ADVANT (Candesartan cilexetil) also has an added effect on these outcomes when used with an ACE inhibitor.
MECHANISM OF ACTION: Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kinase II). Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation and renal re-absorption of sodium. Candesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is, therefore, independent of the pathways for angiotensin II synthesis. Candesartan cilexetil is rapidly converted to the active drug, candesartan,by ester hydrolysis during absorption from the gastrointestinal tract. Candesartan is an angiotensin II receptor antagonist, selective for AT1receptors, with tight binding to and slow dissociation from the receptor. It has no agonist activity. ACE inhibitors also inhibit the degradation of bradykinin, a reaction also catalyzed by ACE. Because candesartan does not inhibit ACE (kinase II), it does not affect the response to bradykinin. Candesartan does not bind to or block other hormone receptors or ion channels known to be important in cardio vascular regulation. Blockade of the angiotensin II receptor inhibits the negative regulatoryfeedback of angiotensin II on renin secretion, but the resulting increased plasma renin activity and angiotensin II circulating levels do not overcome the effect of candesartan on blood pressure. - How to use
- DOSAGE AND ADMINISTRATION: Hypertension- Adults Dosage must be individualized. Response is dose related over the range of 2 to 32 mg. The usual recommended starting dose of ADVANT(Candesartan cilexetil) is 16 mg once daily when it is used as mono-therapy in patients who are not volume depleted. ADVANT (Candesartan cilexetil) can be administered once or twice daily with total daily doses ranging from 8 mg to 32 mg. Most of the antihypertensive effect is present within 2 weeks and maximal blood pressure reduction is generally obtained within 4 to 6weeks of treatment with ADVANT( Candesartan cilexetil ). ADVANT (Candesartan cilexetil) may be administered with or without food. Pediatrics: ADVANT (Candesartan cilexetil) may be administered once daily or divided into two equal doses. Adjust the dosage according to blood pressure response. For patients with possible depletion of intravascular volume (e.g.,patients treated with diuretics, particularly those with impaired renal function) ,initiate ADVANT (Candesartan cilexetil) under close medical supervision and consider administration of a lower dose.
Children 1 to <6 years of age: The dose range is 0.05 to 0.4 mg/kg per day. The recommended starting dose is 0.20 mg/kg.
Children 6 to <17 years of age: For those less than 50 kg, the dose range is 2 to 16 mg per day. The recommended starting dose is 4 to 8 mg. For those greater than 50 kg, the dose range is 4 to 32 mg per day. The recommended starting dose is 8 to 16 mg. An antihypertensive effect is usually present within 2 weeks, with full effect generally obtained within 4 weeks of treatment with ADVANT (Candesartan cilexetil). Children < 1 year of age must not receive ADVANT (Candesartan cilexetil) for hypertension.
Heart Failure: The recommended initial dose for treating heart failure is 4 mg once daily. The target dose is 32 mg once daily, which is achieved by doubling thedose at approximately 2-week intervals, as tolerated by the patient. - Precautions
- CONTRAINDICATIONS: Candesartan cilexetil is contraindicated in patients who are hypersensitive to this drug or any component of this product.
WARNINGS / PRECAUTIONS: General -As with any antihypertensive agent, excessive blood pressure decrease in patients with ischaemic cardiopathy or ischaemic cerebrovascular disease could result in a myocardial infarction or stroke.
Advenza Capsules 30’s
KShs 2,900.00- Description
- Advenza has various formulations like Enzymes+Probiotics, Probiotics with Extracts, standalone Probiotics. It has various application ranging from Gut health, digestion, immunity and women’s health.
- Benefits
- Probiotics helps renew the Gut with useful Bacteria which aids digestion and help maintain immunity.
- How to use
- Take one capsules daily
Aerius 5mg Tablets 30’s
KShs 3,460.00- Description
- Aerius tablets contain Desloratadine 5 mg which is used in the treatment of allergy symptoms. It is an antihistamine medication. It treats allergy symptoms such as such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.
- How to use
- Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aerius 5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
- Precautions
- Aerius 5 mg Tablet may cause excessive drowsiness and calmness with alcohol. Aerius may be unsafe to use during pregnancy. Aerius 5 mg Tablet should be used with caution in patients with kidney and liver disease. Dose adjustment may be needed. Please consult your doctor.
Alatrol Syrup 5mg/5ml 60ml
KShs 150.00- Description
- Alatrol Syrup contains Cetirizine which is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
- How to use
- Shake well before use. Alatrol Syrup may be taken with or without food, but it is better to take it at a fixed time.Adults and children 6 years and older: 5 ml or 10 ml once daily depending upon severity of symptoms; do not take more than 10 ml in 24 hours. Children 2 to under 6 years of age:2.5 ml once daily; if needed, dose can be increased to a maximum of 5 ml once daily or 2.5 ml every 12 hours. Do not give more than 5 ml in 24 hours.
- Precautions
- Do not take cetirizine if you are allergic (hypersensitive) to cetirizine or any of the other ingredients of cetirizine tablet. If you have severe kidney problem or severe liver problem.
Alcomet 500mg Tablets 30’s
KShs 3,920.00- Description
- Alcomet 500 is a drug used to treat some liver-related diseases such as: alcohol intoxication, fatty liver
- Ingredients
- Metadoxine
Aldomet 500mg Tablets 30’s
KShs 1,270.00- Description
- ALDOMET (Methyldopa) is an antihypertensive drug. Methyldopa, the L-isomer of alpha-methyldopa, is levo-3-(3,4-dihydroxyphenyl)-2-methylalanine. Its empirical formula is C10H13NO4, with a molecular weight of 211.22. ‘Aldomet’ Tablets 500 mg, contain methyldopa equivalent to 500 mg anhydrous methyldopa. Inactive ingredients in the tablets are: calcium di-sodium edetate, cellulose, citric acid, colloidal silicon dioxide, D&C Yellow 10, ethylcellulose, guar gum, hydroxypropyl methylcellulose, iron oxide, magnesium stearate, propylene glycol, talc, and titanium dioxide.
- How to use
- Use in adults:
Initial dosage: Usually 250 mg two or three times a day, for two days. Adjustment: Usually adjusted at intervals of not less than two days, until an adequate response is obtained. The maximum recommended daily dosage is 3 g. Many patients experience sedation for two or three days when therapy with ‘Aldomet’ is started or when the dose is increased. When increasing the dosage, therefore, it may be desirable to increase the evening dose first. Withdrawal of ‘Aldomet’ is followed by return of hypertension, usually within 48 hours. This is not complicated generally by an overshoot of blood pressure.
Patients with renal impairment:Methyldopa is largely excreted by the kidney, and patients with impaired renal function may respond to smaller doses.
Other antihypertensives:Therapy with ‘Aldomet’ may be initiated in most patients already on treatment with other antihypertensive agents by terminating these antihypertensive medications gradually, as required. Following such previous antihypertensive therapy, ‘Aldomet’ should be limited to an initial dose of not more than 500 mg daily and increased as required at intervals of not less than two days. When methyldopa is given to patients on other antihypertensives the dose of these agents may need to be adjusted to effect a smooth transition.
When 500 mg of ‘Aldomet’ is added to 50 mg of hydrochlorothiazide, the two agents may be given together once daily.
Paediatric population: initial dosage is based on 10 mg/kg of bodyweight daily in 2-4 oral doses. The daily dosage is then increased or decreased until an adequate response is achieved. The maximum dosage is 65 mg/kg or 3.0 g daily, whichever is less. - Precautions
- Contraindications: ‘Aldomet’ is contra-indicated in patients with:• active hepatic disease, such as acute hepatitis and active cirrhosis.• hypersensitivity to the active substance (including hepatic disorders associated with previous methyldopa therapy), or to any of the excipients listed.• depression.• on therapy with monoamine oxidase inhibitors (MAOIs).• with a catecholamine-secreting tumour such as phaeochromocytoma or paraganglioma.• with porphyria.
Alerid Syrup 30ml
KShs 100.00- Description
- Alerid Syrup is given to children to treat various symptoms such as watery eyes, runny nose, sneezing, and itching associated with allergic conditions like hay fever, urticaria (hives), conjunctivitis (red, itchy eye), and common cold.
- Ingredients
- Cetirizine (5mg/5ml)
- How to use
- Give this medicine to your child orally with or without food in the dose, time, and way prescribed by your child’s doctor.
Alicton Ear Spray 10ml
KShs 729.00- Description
- Alicton Ear Spray is a user-friendly and effective solution for managing ear conditions. It is self-administered without the need for head tilting, and its spray mechanism ensures even coverage of the target area. Suitable for adults and children aged 2 years and above
- Ingredients
- Paradichlorobenzene 2%w/v, Benzocaine 2.7%w/v, Chlorbutol 5%w/v, Turpentine Oil 15%w/v & Olive Oil.
- Benefits
- a) Excessive earwax,
b) Mild ear infections: Swimmer’s ear (otitis external),
c) Discomfort, & mild pain, including post-procedure,
d) Minor traumatic ear injuries from inserting foreign objects, improper earbud use, or hearing aids,
e) A hydrant for dryness, including cracking, caused by cold weather.
f) Ear ringing,
g) Itching due to allergic reactions, including scratching resulting in minor injuries,
h) Pre-syringing / Pre-irrigation. - How to use
- Administer 1 spray for pediatric patients and up to 3 sprays for adults, twice daily for 7 days.
- Precautions
- Avoid in perforated eardrum.
Use externally only.
Alison Antibacterial Handwash 600ml
KShs 251.00- Description
- Alison Moisturising Hand Wash Aloe Vera cleans hands and leaves them soft, smooth and pleasantly fragranced.
Alison Coconut Massage Oil 200ml
KShs 348.00- Description
- Alison Coconut Massage Oil is part of a luxurious and restorative experience and is used for massage purposes, leaving your skin feeling soft. This organic, cold pressed, virgin coconut oil contains no chemicals and smells delightfully of coconuts. It can be mixed with other scented natural oils for an added aromatherapy experience. It has no toxic side-effects and because of its high saturated fat content is very smooth and moisturising. It does not irritate delicate skin and a small amount goes a long way, making it very economical.
Alison Ideal Eucalyptus Oil 50ml
KShs 459.00- Description
- The Ideal Eucalyptus Oil is a natural antiseptic with antifungal, antiviral, anti-inflammatory, and antibacterial properties, making it highly effective in treating wounds, minor cuts, acne, boils, insect bites and skin infections. Eucalyptus Essential Oil is a purifying, cleansing, clarifying, and immune-boosting oil that is ideal for use on skin, in aromatherapy, and as a surface cleaning agent and a fabric freshener. It is used in aromatherapy, the cooling scent of Eucalyptus Essential Oil is known to relieve mental exhaustion by boosting circulation to the brain, thereby stimulating the mind out of sluggishness, and rejuvenating the spirit. Those suffering from sinus congestion can diffuse Eucalyptus Essential Oil in the bedroom throughout the night to clear nasal passages and to eliminate harmful airborne bacteria that contribute to the feeling of being unwell.
- How to use
- For relief from congestion, mix a few drops in a steaming bowl of hot water and lean over it to inhale the aromatic vapors with a towel draped over the head and bowl for a few minutes. The eyes should be closed to prevent irritation. It has traditionally been used to relieve the discomforts associated with fatigue, headaches, colds, sinusitis, mucous congestion, muscle aches and pains, and asthma.
- Precautions
- As per NAHA guidelines, New Directions Aromatics (NDA) does not recommend the ingestion of essential oils. Pregnant and nursing women are particularly cautioned to avoid using the essential oil without medical guidance.
Alison Ideal Rose water & Glycerine 200ml
KShs 118.00- Description
- Alison (Ideal) Rose water with Glycerine 200ml is pleasantly scented natural astringent for skin softening. It helps to tighten the pores, rids the skin of excess oils and gently tones the skin leaving you with an even matte complexion.